Our Foundation

The UPMC Genome Center is a high-throughput, industrial-scale sequencing center located in Pittsburgh, PA. We are one of the few sequencing centers that is both CAP accredited and CLIA certified, speaking to the highest quality laboratory standards.

We use a secure and compliant data management and analysis platform that is entirely cloud-based allowing for rapid data processing using the most advanced tools in the industry. Our lab deploys analysis pipelines incorporating state-of-the-art software and hardware tools for fast, flexible, and compute-intensive data processing.

By pairing this advanced technology with our in-house team of bioinformatics experts and cutting-edge sequencing machines, the Genome Center is prepared to provide the most accurate results in the shortest amount of time.


The UPMC Genome Center’s mission is to provide the highest quality DNA and RNA analysis services to support physicians in helping their patients. We support our research collaborators in their pursuit of understanding DNA and RNA sequence variations in relation to the phenotypic variability in human disease.

Photo of DNA analysis hardware

Photo of analytst reviewing DNA data on a computer

Expert-Driven Outputs

Our team consists of professionally-trained, certified and experienced lab technicians and bioinformaticians who work tirelessly to assist with requests from small to large-scale projects. Our team works closely with our clients to provide high-quality sequencing services.

Photo of machines in the Genome Center lab

The Lab

Based in the heart of Pittsburgh’s technology hub, the Genome Center is both a CAP and CLIA certified lab employing the latest sequencing technologies and the highest quality of bioinformatic analyses. We provide quality, automated laboratory services for whole genome, whole exome and whole transcriptome sequencing employing numerous robotic liquid handlers and a variety of sequencing platforms (incl, Illumina’s NovaSeq 6000 series).